Synthetic ease and exceptional <i>in vivo</i> performance of pyrazole-based cyclometallated iridium complexes
Marta Redrado, Eduardo Romanos, Andrea Benedi, Guillermo Canudo‐Barreras, Isabel Marzo, M. Concepción Gimeno, Vanesa Fernández‐Moreira
Abstract
Novel cyclometallated Ir III complexes, exhibiting dual functionality as potent anticancer agents and photosensitisers, with selective efficacy against specific cancer cell lines.
Topics & Concepts
IridiumPyrazoleIn vivoCombinatorial chemistryChemistryCancer cell linesCancer researchCancerStereochemistryCancer cellBiochemistryBiologyCatalysisGeneticsMetal complexes synthesis and propertiesOrganic Light-Emitting Diodes ResearchClick Chemistry and Applications