Cerium oxide nanozyme attenuates periodontal bone destruction by inhibiting the ROS–NFκB pathway
Yijun Yu, Sheng Zhao, Deao Gu, Bijun Zhu, Hanxiao Liu, Wenlei Wu, Jiangjiexing Wu, Hui Wei, Leiying Miao
Abstract
A detailed anti-inflammatory mechanism study of CeO 2 nanozymes with reactive oxygen species scavenging abilities toward periodontitis treatment advances future nanozyme-based clinical applications.
Topics & Concepts
PeriodontitisReactive oxygen speciesChemistryInflammationBone resorptionOsteoclastOxidative stressDental alveolusNanotoxicologyCell biologyPharmacologyIn vitroImmunologyBiochemistryMedicineDentistryBiologyToxicityInternal medicineOrganic chemistryAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniquesNanoparticles: synthesis and applications