Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs
Yihua Pei, Yanjie Bao, Cristiano Sacchetti, Juthamart Brady, Kyra Gillard, Hailong Yu, Scott Roberts, Kumar Rajappan, Steven P. Tanis, Carlos G. Pérez‐García, Padmanabh Chivukula, Priya Karmali
Topics & Concepts
ChemistryTransfectionCytotoxicityGene deliveryIn vitroAerosolizationMessenger RNADelivery systemPharmacologyBiochemistryInhalationGeneMedicineAnatomyRNA Interference and Gene DeliveryAdvanced Drug Delivery SystemsClinical Nutrition and Gastroenterology