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Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm

Yun Young Lee, Hee Ho Park, Wooram Park, Hyelim Kim, Jong Geol Jang, Kyung Soo Hong, Jae‐Young Lee, Hee Seung Seo, Dong Hee Na, Tae Hyung Kim, Young Bin Choy, June Hong Ahn, Wonhwa Lee, Chun Gwon Park

2020Biomaterials169 citationsDOIOpen Access PDF

Topics & Concepts

Cytokine stormSepsisCytokineARDSCoronavirusCytokine release syndromeImmunologyMedicineNeutrophil extracellular trapsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Respiratory distressInflammationLungDiseaseInternal medicineInfectious disease (medical specialty)AnesthesiaNeutrophil, Myeloperoxidase and Oxidative MechanismsSepsis Diagnosis and TreatmentCOVID-19 Clinical Research Studies
Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm | Litcius