CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides
Guillaume Gaud, Sooraj Achar, François X. P. Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S. Hinrichs, Dorian B. McGavern, Paul François, Grégoire Altan‐Bonnet, Paul E. Love
Topics & Concepts
Immunoreceptor tyrosine-based activation motifT-cell receptorCD3BiologyCell biologyT cellSignal transductionCD8AntigenImmune systemImmunologyCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology