Comparison of Isomerase and Weimberg Pathway for γ-PGA Production From Xylose by Engineered Bacillus subtilis
Birthe Halmschlag, Kyra Hoffmann, René Hanke, Sastia Prama Putri, Eiichiro Fukusaki, Jochen Büchs, Lars M. Blank
Abstract
The production of poly--glutamic acid (-PGA), a biopolymer consisting of D-and L-glutamic acid monomers, currently relies on L-glutamate, or citrate as carbon substrates. Here we aimed at using plant biomass-derived substrates such as xylose.
Topics & Concepts
Bacillus subtilisXyloseXylose isomeraseChemistryIsomeraseBiochemistryMicrobiologyBiologyEnzymeBacteriaFermentationGeneticsBiopolymer Synthesis and ApplicationsBiofuel production and bioconversionEnzyme Production and Characterization