Streptocyanine as an activation mode of amine catalysis for the conversion of pyridine rings to benzene rings
Tatsuya Morofuji, Shota Nagai, Airi Watanabe, Kota Inagawa, Naokazu Kano
Abstract
a ring-closing reaction, thereby releasing the amine catalyst. Consequently, the alkene moiety in the starting pyridines is incorporated into the benzene ring of the products. Pyridiniums bearing various alkene moieties were efficiently converted to formyl-substituted benzene derivatives. Mechanistic studies support the postulation that the present catalytic process was intermediated by streptocyanine. In this reaction system, streptocyanine could be regarded as a new activation mode of amine catalysis.
Topics & Concepts
BenzenePyridineChemistryAmine gas treatingConjugated systemCatalysisRing (chemistry)PhotochemistryMedicinal chemistryPolymer chemistryOrganic chemistryPolymerCatalytic C–H Functionalization MethodsOxidative Organic Chemistry ReactionsSynthesis and Characterization of Pyrroles