Novel hypoxia-induced HIF1α-circTDRD3-positive feedback loop promotes the growth and metastasis of colorectal cancer
Zhongmao Fu, Pengshan Zhang, Renchao Zhang, Bimeng Zhang, Shijun Xiang, Yuan Zhang, Zai Luo, Chen Huang
Topics & Concepts
Colorectal cancerBiologyCancer researchHIF1AMetastasisHypoxia (environmental)microRNADownregulation and upregulationCell growthTumor progressionCancerBiomarkerTumor hypoxiaIn vivoMalignancyAngiogenesisInternal medicineGeneMedicineGeneticsRadiation therapyChemistryOxygenOrganic chemistryCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research