Insights into non-peptide small-molecule inhibitors of the PD-1/PD-L1 interaction: Development and perspective
Xia Wu, Yangyang Meng, Lei Liu, Guowei Gong, Haotian Zhang, Yunlei Hou, Chunyang Liu, Di Wu, Mingze Qin
Topics & Concepts
PeptidomimeticChemistrySmall moleculePembrolizumabPeptideNivolumabCancer immunotherapyMonoclonal antibodyDocking (animal)Combinatorial chemistryImmunotherapyPharmacologyComputational biologyImmune systemStereochemistryBiochemistryAntibodyImmunologyMedicineNursingBiologyCancer Immunotherapy and BiomarkersPeptidase Inhibition and AnalysisCAR-T cell therapy research