Repurposed antipsychotic chlorpromazine inhibits colorectal cancer and pulmonary metastasis by inducing G2/M cell cycle arrest, apoptosis, and autophagy
Fuyan Xu, Huizhi Xi, Mengya Liao, Yiqian Zhang, Hongbo Ma, Meng‐Ling Wu, Qiang Xue, Hongbao Sun, Yiwen Zhang, Yong Xia
Topics & Concepts
ApoptosisCyclin-dependent kinase 1Cell cycle checkpointCancer researchCell cycleAutophagyMetastasisPharmacologyMedicineCancer cellColorectal cancerCancerBiologyInternal medicineBiochemistryAutophagy in Disease and TherapyCancer, Stress, Anesthesia, and Immune ResponseCancer Mechanisms and Therapy