Discovery of <i>N</i>-Phenylaminomethylthioacetylpyrimidine-2,4-diones as Protoporphyrinogen IX Oxidase Inhibitors through a Reaction Intermediate Derivation Approach
Dawei Wang, Lu Liang, Zhi-Yuan Xue, Shuyi Yu, Ruibo Zhang, Xia Wang, Han Xu, Xin Wen, Zhen Xi
Abstract
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Topics & Concepts
Protoporphyrinogen oxidaseChemistryTrifluoromethylRing (chemistry)Thio-StereochemistryHydrogen bondCombinatorial chemistryEnzymeOrganic chemistryMoleculeAlkylFungal Plant Pathogen ControlWeed Control and Herbicide ApplicationsPesticide and Herbicide Environmental Studies