Methylene blue as a far-red light-mediated photocleavable multifunctional ligand
Huy M. Dao, Chang‐Hee Whang, Vijay Kumar Shankar, Yan‐Hong Wang, Ikhlas A. Khan, Larry Walker, Islam Husain, Shabana I. Khan, S. Narasimha Murthy, Seongbong Jo
Abstract
Methylene blue (MB) with a 10-N-carbamoyl linkage was discovered and developed as a multifunctional far-red (660 nm) photocleavable ligand capable of rendering a series of MB-conjugated compounds with off-to-on fluorescence switch properties through the controlled release of MB.
Topics & Concepts
Methylene blueConjugated systemChemistryFluorescenceLigand (biochemistry)Red lightMethylenePhotochemistryPhotodynamic therapyCombinatorial chemistryMoleculeFar-redOrganic chemistryReceptorBiochemistryPolymerPhotocatalysisCatalysisQuantum mechanicsBotanyPhysicsBiologyPhotochromic and Fluorescence ChemistryRadical Photochemical ReactionsClick Chemistry and Applications