Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
Jiasheng Zhang, Dmitry Velmeshev, Kei Hashimoto, Yu‐Hsin Huang, Jeffrey W. Hofmann, Xiaoyu Shi, Jiapei Chen, Andrew M. Leidal, Julian G. Dishart, Michelle K. Cahill, Kevin W. Kelley, Shane A. Liddelow, William W. Seeley, Bruce L. Miller, Tobias C. Walther, Robert V. Farese, J. Paul Taylor, Erik M. Ullian, Bo Huang, Jayanta Debnath, Torsten Wittmann, Arnold R. Kriegstein, Eric J. Huang
Topics & Concepts
NeurodegenerationMicrogliaFrontotemporal lobar degenerationBiologyCell biologyNeuroscienceRNAGeneFrontotemporal dementiaInflammationDiseaseGeneticsPathologyImmunologyMedicineDementiaAmyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms