Near-infrared fluorescence imaging-guided focused ultrasound-mediated therapy against Rheumatoid Arthritis by MTX-ICG-loaded iRGD-modified echogenic liposomes
Haohan Wu, Yanni He, Hao Wu, Meijun Zhou, Zhili Xu, Ran Xiong, Fei Yan, Hongmei Liu
Abstract
Our study provides a promising nanoplatform for integrating ultrasound-controlled drug release and NIR fluorescence imaging for RA treatment.
Topics & Concepts
Rheumatoid arthritisLiposomeEchogenicityMedicineIndocyanine greenUltrasoundFluorescenceFluorescence-lifetime imaging microscopyMolecular imagingRadiologyChemistryPathologyInternal medicineIn vivoBiochemistryOpticsBiologyBiotechnologyPhysicsRheumatoid Arthritis Research and TherapiesUltrasound and Hyperthermia ApplicationsOrthopedic Infections and Treatments