Aspirin ameliorates the cognition impairment in mice following benzo[a]pyrene treatment via down-regulating BDNF IV methylation
Yangyang Li, Jingjing Cao, Zhongsuo Hao, Aixiang Liu, Xin Li, Huan Li, Na Xia, Zemin Wang, Zhihong Zhang, Jianying Bai, Hongmei Zhang
Topics & Concepts
NeurotoxicityBrain-derived neurotrophic factorBenzo(a)pyreneAspirinNeurotrophic factorsHippocampusDNA methylationChemistryPharmacologyMethylationEndocrinologyTropomyosin receptor kinase BInternal medicineMedicinePyreneToxicityBiochemistryGene expressionReceptorGeneOrganic chemistryEpigenetics and DNA MethylationPrenatal Substance Exposure EffectsNeurogenesis and neuroplasticity mechanisms