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The inhibitory effect of Astragalus flavone extract on hyperuricemia and its underlying molecular mechanism by targeting JNK/AP-1/NLRP3/IL-1β signaling pathway

Hongjuan Xia, Wenjiang He, Chenghao Lv, Jieyan Zhang, Xuan Lin, Si Qin

2025Phytomedicine11 citationsDOI

Topics & Concepts

HyperuricemiaAstragalusMechanism (biology)Traditional medicineChemistryPharmacologySignal transductionInhibitory postsynaptic potentialBiologyMedicineBiochemistryUric acidTraditional Chinese medicineEndocrinologyAlternative medicineEpistemologyPathologyPhilosophyGout, Hyperuricemia, Uric AcidTraditional Chinese Medicine AnalysisNephrotoxicity and Medicinal Plants
The inhibitory effect of Astragalus flavone extract on hyperuricemia and its underlying molecular mechanism by targeting JNK/AP-1/NLRP3/IL-1β signaling pathway | Litcius