Interaction of<i>FKBP5</i>variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex
Anja Richter, Mohammad Al-Bayati, Foteini Paraskevopoulou, Bernd Krämer, Jens C. Pruessner, Elisabeth B. Binder, Oliver Gruber
Abstract
rs3800373 minor risk allele in predisposing those who live in bigger cities to changes of functional responsivity in the pre- and subgenual ACC, thereby increasing the risk for developing stress-related mental disorders.
Topics & Concepts
FKBP5Anterior cingulate cortexAmygdalaFunctional magnetic resonance imagingNeuroscienceGlucocorticoid receptorMedicinePsychologyMood disordersAnxietyClinical psychologyPsychiatryInternal medicineGlucocorticoidCognitionStress Responses and CortisolHormonal Regulation and HypertensionTryptophan and brain disorders