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Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection

Cory J. Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J.C. Lin, Ying K. Tam, Drew Weissman, Norbert Pardi, Luis J. Sigal

2021Molecular Therapy42 citationsDOIOpen Access PDF

Topics & Concepts

Ectromelia virusVirologyBiologyLymphocytic choriomeningitisCytotoxic T cellCD8VirusEpitopeT cellAntibodyImmunologyImmune systemGeneVacciniaRecombinant DNABiochemistryIn vitroImmunotherapy and Immune ResponsesAnimal Virus Infections StudiesVirus-based gene therapy research
Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection | Litcius