Novel benzenesulfonamide derivatives as potential selective carbonic anhydrase IX, XII inhibitors with anti-proliferative activity: Design, synthesis and in silico studies
Wael A. A. Fadaly, Fatma El Zahraa Ammar Mohamed, Mohamed T. M. Nemr, Ahmed M. Sayed, Rehab G. Khalil, Taha H. Zidan
Topics & Concepts
ChemistryIn silicoCarbonic anhydraseSulfonamideCombinatorial chemistryBiochemistryCarbonic anhydrase IIPharmacologyEnzymeStereochemistryGeneMedicineEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities