Off target toxicities and links with physicochemical properties of medicinal products, including antibiotics, oligonucleotides, lipid nanoparticles (with cationic and/or anionic charges). Data review suggests an emerging pattern
Sarah Gould, Michael V. Templin
Topics & Concepts
Cationic polymerizationOligonucleotideChemistryAntibioticsCombinatorial chemistrySolid lipid nanoparticleNanoparticlePharmacologyNanotechnologyMedicineBiochemistryMaterials scienceOrganic chemistryDNAAntimicrobial Peptides and ActivitiesRNA Interference and Gene DeliveryLipid Membrane Structure and Behavior