A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxamer
Sudong Chae, Seungbae Oh, Kyung Hwan Choi, Jin Woong Lee, Jiho Jeon, Zhixiang Liu, Cong Wang, Changmo Lim, Xue Dong, Chaeheon Woo, Ghulam Asghar, Liyi Shi, Joohoon Kang, Sung‐Jae Kim, Si Young Song, Jung Heon Lee, Hak Ki Yu, Jae‐Young Choi
Abstract
Abstract In this research, dispersion of a new type of one-dimensional inorganic material Nb 2 Se 9 , composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb 2 Se 9 , which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb 2 Se 9 , and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb 2 Se 9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb 2 Se 9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.