Colorimetric Detection of Nucleic Acids through Triplex-Hybridization Chain Reaction and DNA-Controlled Growth of Platinum Nanoparticles on Graphene Oxide
Weiwei Chen, Xiaobo Zhang, Juanjuan Li, Lizhen Chen, Ningning Wang, Siqi Yu, Guangming Li, Linfei Xiong, Huangxian Ju
Abstract
microRNA. This method was validated with better analytical performance than a general HCR system and could be effectively used for the identification of single-nucleotide polymorphisms, thus providing a novel approach for simple and sensitive detection of nucleic acids.
Topics & Concepts
ChemistryNucleic acidChain reactionDNACombinatorial chemistryNanomaterialsCatalysisDetection limitGrapheneNanotechnologyBiosensorNanoparticleBiochemistryChromatographyPhotochemistryMaterials scienceAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniquesNanocluster Synthesis and Applications