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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood

Tamás Kiss, Stefano Tarantini, Tamás Csípő, Priya Balasubramanian, Ádám Nyúl‐Tóth, Andriy Yabluchanskiy, Jonathan D. Wren, Lori Garman, Derek M. Huffman, Anna Csiszár, Zoltán Ungvári

2020GeroScience69 citationsDOIOpen Access PDF

Topics & Concepts

ParabiosisTranscriptomeOxidative stressHeterochronyBiologyEndothelial dysfunctionRejuvenationEndotheliumInternal medicineEndocrinologyCell biologyMedicineGene expressionGeneGeneticsOntogenyGenetics, Aging, and Longevity in Model OrganismsSpaceflight effects on biologyPhysiological and biochemical adaptations
Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood | Litcius