Leveraging efferocytosis blockade for improved cancer chemo-immunotherapy through synchronized release of doxorubicin and BMS777607 confined within tailored mesoporous silica nanoparticles
Jingyang Zhang, Fangman Chen, Yuxuan Li, Qi-Jia Duan, Chong Wu, Sui-Juan Zheng, Kam W. Leong, Dan Shao, Jin‐Zhi Du
Topics & Concepts
EfferocytosisDoxorubicinCancer researchImmunotherapyTumor microenvironmentBlockadeCancerCancer immunotherapyMesoporous silicaImmune checkpointMetastasisCancer cellPharmacologyChemotherapyMedicineChemistryReceptorInternal medicineMacrophageMesoporous materialTumor cellsBiochemistryIn vitroCatalysisPhagocytosis and Immune RegulationNanoplatforms for cancer theranosticsImmune cells in cancer