Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1H)-quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents
Baihui Li, Yangli Shen, Hu Wu, Xiaobo Wu, Lvjiang Yuan, Qinggang Ji
Topics & Concepts
PotencyCandida albicansChemistryChitin synthaseChitinAntifungalIC50StereochemistryAntimicrobialCorpus albicansEnzymeBiochemistryFluconazoleIn vitroMicrobiologyBiologyOrganic chemistryYeastChitosanPhytochemical compounds biological activitiesPlant-Microbe Interactions and ImmunityFungal Plant Pathogen Control