iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers
Shanliang Zheng, Xingwen Wang, Hao Liu, Dong Zhao, Qingyu Lin, Qinghua Jiang, Li Li, Ying Hu
Topics & Concepts
Unfolded protein responseDownregulation and upregulationEndoplasmic reticulumProgrammed cell deathCancer researchOncogeneUbiquitin ligaseApoptosisColorectal cancerBiologyCancerCell biologyUbiquitinCell cycleBiochemistryGeneticsGeneEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyHeat shock proteins research