Decreased RNA m<sup>6</sup>A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
Min Tao, Xiaoyu Li, Lei He, Xiaoming Rong, Hongxuan Wang, Jingrui Pan, Zijing Lu, Xiaoni Zhang, Ying Peng
Abstract
A methylation suppresses the process of EMT and VM in glioblastoma, providing a new perspective to seek for a potential therapeutic target for GB.
Topics & Concepts
Vasculogenic mimicryCancer researchBiologyRNAVimentinMethylationGliomaEpithelial–mesenchymal transitionMessenger RNARNA methylationMethyltransferaseCell biologyDownregulation and upregulationImmunohistochemistryImmunologyGeneCancerGeneticsMetastasisRNA modifications and cancerCancer-related molecular mechanisms researchCircular RNAs in diseases