Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA
Theresa Kissel, Tineke J van Wesemael, Anders Lundquist, Heidi Kokkonen, Atsushi Kawakami, Mami Tamai, Dirkjan van Schaardenburg, Manfred Wuhrer, T. Huizinga, Hans Ulrich Scherer, Diane van der Woude, Solbritt Rantapää‐Dahlqvist, René E. M. Toes
Topics & Concepts
Somatic hypermutationImmunologyAutoantibodyAntibodyRheumatoid factorHuman leukocyte antigenMedicineGlycosylationEpitopeAlleleRheumatoid arthritisGlycanAntigenB cellBiologyGeneGeneticsGlycoproteinMonoclonal and Polyclonal Antibodies ResearchT-cell and B-cell ImmunologySystemic Lupus Erythematosus Research