Lidocaine inhibits the proliferation and invasion of hepatocellular carcinoma by downregulating USP14 induced PI3K/Akt pathway
Yi Zhang, Yi Zhang, Jiankun Jia, Weidong Jin, Jun Cao, Tao Fu, Dandan Ma, Yang Zhang, Yang Zhang
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BVimentinCancer researchEpithelial–mesenchymal transitionApoptosisDownregulation and upregulationChemistrySignal transductionWestern blotBiologyCell biologyImmunologyImmunohistochemistryBiochemistryGeneUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism