Tanshinone IIA attenuates silica-induced pulmonary fibrosis via Nrf2-mediated inhibition of EMT and TGF-β1/Smad signaling
Feifei Feng, Peng Cheng, Shaohua Xu, Nannan Li, Hui Wang, Ying Zhang, Wei Wang
Topics & Concepts
SilicosisSMADPulmonary fibrosisTransforming growth factorOxidative stressEpithelial–mesenchymal transitionChemistryFibrosisWestern blotSignal transductionCancer researchMedicinePharmacologyPathologyDownregulation and upregulationInternal medicineBiochemistryGeneOccupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational exposure and asthma