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LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity

Hui Wang, Jun Cai, Shaoxia Du, Wei Wei, Xiaohong Shen

2020Experimental Cell Research48 citationsDOI

Topics & Concepts

Pancreatic cancerBiologyCell migrationProtein kinase BCell biologyCancer researchExtracellularCancer cellSignal transductionCellLamininExtracellular matrixCancerBiochemistryGeneticsCell Adhesion Molecules ResearchCellular Mechanics and InteractionsCaveolin-1 and cellular processes
LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity | Litcius