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Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway

Eman S. Zaki, Rabab H. Sayed, Muhammed A. Saad, Muhammed F. El-Yamany

2023Life Sciences16 citationsDOI

Topics & Concepts

RoflumilastAMPKAutophagyPI3K/AKT/mTOR pathwayPharmacologyEndocrinologyMedicineInternal medicineChemistryProtein kinase AApoptosisKinaseBiochemistryCOPDPhosphodiesterase function and regulationAutophagy in Disease and TherapyAdenosine and Purinergic Signaling
Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway | Litcius