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Lipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye

Vasudevan Ayyappan, Antony Jozić, Allison Curtis, Emily Bodi, Renee C. Ryals, Gaurav Sahay

2025Journal of Controlled Release16 citationsDOI

Topics & Concepts

Trabecular meshworkGene deliveryGene expressionGlaucomaGenetic enhancementMessenger RNACell biologymCherryBiologyGeneMolecular biologyChemistryOphthalmologyMedicineGeneticsGreen fluorescent proteinRNA Interference and Gene DeliveryRNA regulation and diseaseRetinal Development and Disorders
Lipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye | Litcius