COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway
Ali Mroueh, Walaa Fakih, Adrien Carmona, Antonin Trimaille, Kensuke Matsushita, Benjamin Marchandot, Abdul Wahid Qureshi, Dal-Seong Gong, Cyril Auger, Laurent Sattler, Antje Reydel, Sébastien Hess, Walid Oulehri, Olivier Vollmer, Jean‐Marc Lessinger, Nicolás Meyer, Michael Paul Pieper, Laurence Jesel, Magnus Bäck, Valérie B. Schini‐Kerth, Olivier Morel
Topics & Concepts
Proinflammatory cytokineEndothelial dysfunctionInflammationDownregulation and upregulationOxidative stressImmunologyMedicineWestern blotTumor necrosis factor alphaEndotheliumEndothelial activationThrombogenicityChemistryInternal medicinePlateletBiochemistryGeneCOVID-19 Clinical Research StudiesPlatelet Disorders and TreatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms