Development and Evaluation of Polymeric Mixed Micelles Prepared using Hot-Melt Extrusion for Extended Delivery of Poorly Water-Soluble Drugs
Sheng Feng, Ziru Zhang, Ahmed Almotairy, Michael A. Repka
Topics & Concepts
MicelleSolubilityChemical engineeringExtrusionPoloxamerCrystallinityDispersityChemistryParticle sizeHydrophobeDrug deliveryDifferential scanning calorimetryPoloxamer 407Aqueous solutionMaterials scienceChromatographyPolymerOrganic chemistryCopolymerComposite materialThermodynamicsPhysicsEngineeringDrug Solubulity and Delivery SystemsSurfactants and Colloidal SystemsAdvanced Drug Delivery Systems