Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice
Aoxiang Zhuge, Shengjie Li, Pengcheng Lou, Wenrui Wu, Kaiceng Wang, Yin Yuan, Jiafeng Xia, Bo Li, Lanjuan Li
Abstract
This study concentrates on longitudinal alternations of gut microbiota in NAFLD progression and discovers the interrelationships between them. These findings may uncover the role of gut microbiota in NAFLD progression and identify novel noninvasive diagnostic tools for NAFLD based on microbial biomarkers.
Topics & Concepts
Nonalcoholic fatty liver diseaseBiologyGut flora16S ribosomal RNAMetagenomicsDiseaseRibosomal RNAGeneticsMicrobiologyGeneFatty liverImmunologyMedicineInternal medicineLiver Disease Diagnosis and TreatmentGut microbiota and healthDiet and metabolism studies