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Structure–activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents

Tianyun Fan, Yuxin Yang, Qingxuan Zeng, Xuelei Wang, Wei Wei, Xixi Guo, Liping Zhao, Danqing Song, Yanxiang Wang, Li Wang, Bin Hong

2021Bioorganic Chemistry24 citationsDOI

Topics & Concepts

PCSK9KexinBerberineChemistryProprotein convertaseLDL receptorSubtilisinIn vivoPharmacologyBiochemistryLipoproteinCholesterolEnzymeBiologyBiotechnologyLipoproteins and Cardiovascular HealthBerberine and alkaloids researchMicrobial Metabolism and Applications
Structure–activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents | Litcius