CD27 agonism coordinates with CD28 and 4-1BB signal to augment the efficacy of CAR-T cells in colorectal tumor
Chengcheng Zhang, Jiankun Jia, Gang Heng, Yunyan Li, Meilin Wang, Jun Chen, Linling Wang, Di Jiang, Zhi Yang, Cheng Qian
Topics & Concepts
CD28Chimeric antigen receptorStimulationCo-stimulationT cellCD8Cancer researchAntigenMedicineCytotoxic T cellInternal medicineImmune systemImmunologyBiologyChemistryIn vitroBiochemistryCAR-T cell therapy researchNanowire Synthesis and ApplicationsImmune Cell Function and Interaction