Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs
Jia Xuan Kee, Jia Ning Nicolette Yau, Ram Pravin Kumar Muthuramalingam, Xinyi Wang, Wei Heng Chng, Alvaro Lopez‐Sanchez, Kevin Tay, Lih‐Wen Deng, Dan Gibson, Hélène Bertrand, Giulia Adriani, Wee Han Ang, Giorgia Pastorin
Abstract
systems in CRC research. Overall, the review advocates for a comprehensive approach, integrating prevention, early detection, and personalized treatments to alleviate the global burden of CRC.
Topics & Concepts
OxaliplatinColorectal cancerMedicineDrugIntensive care medicineChemotherapyOncologyCancerDrug resistanceInternal medicineHarmBioinformaticsProdrugIncidence (geometry)PharmacogeneticsPublic healthEfficacyMEDLINEFluorouracilReview articlePharmacologyCause of deathDrug developmentPrecision medicineColorectal Cancer Treatments and StudiesCancer Treatment and PharmacologyGenetic factors in colorectal cancer