Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling
Friedrich Hahn, Aischa Niesar, Christina Wangen, Markus Wild, Benedikt W. Grau, Lars Herrmann, Aysun Çapcı, Annie Adrait, Yohann Couté, Svetlana B. Tsogoeva, Manfred Marschall
Topics & Concepts
ArtesunateClick chemistryHuman cytomegalovirusIn vitroAntiviral drugIn vivoChemistryFluorescence microscopeBiochemistryBiologyCell biologyDrugFluorescencePharmacologyCombinatorial chemistryPlasmodium falciparumGeneImmunologyMalariaQuantum mechanicsBiotechnologyPhysicsCytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatmentsinterferon and immune responses