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Safety and effectiveness of vonoprazan-based rescue therapy for <i>Helicobacter pylori</i> infection

Jing Yu, Yiming Lv, Peng Yang, Yizhou Jiang, Xiang‐Rong Qin, Xiaoyong Wang

2023World Journal of Gastroenterology10 citationsDOIOpen Access PDF

Abstract

BACKGROUND: ) infection. However, their value as a rescue therapy needs to be explored. AIM: rescue therapy. METHODS: C-urea breath test, and factors associated with eradication success were explored. RESULTS: = 0.025). No severe adverse events occurred; most adverse events were mild and disappeared without intervention. Good compliance was seen in 95.6% (65/68) patients. Serological examination showed no significant changes in liver and kidney function. CONCLUSION: VAS is a safe and effective rescue therapy, with an acceptable eradication rate (> 90%), regardless of the number of prior treatment failures. Anxiety may be associated with eradication failure.

Topics & Concepts

MedicineAmoxicillinInternal medicineRegimenHelicobacter pyloriLevofloxacinBreath testSaccharomyces boulardiiClarithromycinMetronidazoleAdverse effectUrea breath testGastroenterologyAntibioticsHelicobacter pylori infectionMicrobiologyProbioticBiologyBacteriaGeneticsHelicobacter pylori-related gastroenterology studiesVeterinary medicine and infectious diseasesGastric Cancer Management and Outcomes
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