Litcius/Paper detail

VCP/p97 regulates Beclin-1-dependent autophagy initiation

Sandra Malmgren Hill, Lidia Wróbel, Avraham Ashkenazi, Marian Fernandez-Estévez, Keith Tan, Roland W. Bürli, David C. Rubinsztein

2021Nature Chemical Biology147 citationsDOIOpen Access PDF

Topics & Concepts

AutophagyCell biologyAutophagosomeULK1BiogenesisChemistryPI3K/AKT/mTOR pathwayBAG3NeurodegenerationRegulatorPhosphatidylinositolKinaseBiologySignal transductionProtein kinase ABiochemistryApoptosisGenePathologyAMPKMedicineDiseaseAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseLysosomal Storage Disorders Research