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Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy

Rebecca L. Best, Nichole E. LaPointe, Olga Azarenko, Herb P. Miller, Christine Genualdi, Stephen Y. Chih, Ben‐Quan Shen, Mary Ann Jordan, Leslie Wilson, Stuart C. Feinstein, Nicola J. Stagg

2021Toxicology and Applied Pharmacology105 citationsDOI

Topics & Concepts

TubulinMicrotubuleBiophysicsIn vitroPayload (computing)ChemistryCell biologyCancer researchMedicineBiologyBiochemistryComputer scienceComputer networkNetwork packetCancer Treatment and PharmacologyMicrotubule and mitosis dynamicsMultiple Myeloma Research and Treatments
Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy | Litcius