New methodological developments for testing the in vitro genotoxicity of nanomaterials: Comparison of 2D and 3D HepaRG liver cell models and classical and high throughput comet assay formats
Julia Varet, Audrey Barranger, Camille Crochet, Sylvie Huet, Kevin Hogeveen, Ludovic Le Hégarat, Valérie Fessard
Topics & Concepts
GenotoxicityComet assayCytotoxicityChemistryNanomaterialsDNA damageLysisViability assayNanotechnologyEnvironmental chemistryBiophysicsDNAMolecular biologyNuclear chemistryIn vitroBiochemistryToxicityBiologyMaterials scienceOrganic chemistryNanoparticles: synthesis and applicationsMicroplastics and Plastic PollutionHeavy Metal Exposure and Toxicity