EGCG attenuates the neurotoxicity of methylglyoxal via regulating MAPK and the downstream signaling pathways and inhibiting advanced glycation end products formation
Yin He, Zhijun Yang, Jingwen Pi, Tiange Cai, Ying Xia, Xiangyu Cao, Jianli Liu
Topics & Concepts
MethylglyoxalNeurotoxicityGlycationMAPK/ERK pathwayChemistryReactive oxygen speciesSignal transductionCell biologyNeuroprotectionApoptosisBiochemistryBlotPharmacologyReceptorBiologyToxicityEnzymeOrganic chemistryGeneAdvanced Glycation End Products researchTea Polyphenols and EffectsNeurological Disease Mechanisms and Treatments