Ultrasensitive detection of butyrylcholinesterase activity based on the inner filter effect of MnO<sub>2</sub> nanosheets on sulfur nanodots
Tianzi Li, Yetong Gao, Huiya Li, Chenyang Zhang, Yifei Xing, Meng Jiao, Yue Shi, Wei Li, Yongqing Zhai, Zhenguang Wang
Abstract
is achieved, which is the best performance so far. The as-proposed assay is robust enough for practical detection in human serum, and it can avoid interference from its sister enzyme (acetylcholinesterase) and glutathione at the micromolar level. The presented results provide a clue for the functionalization of S-dots, and offer a powerful tool as an analytic technique for nanomedicine and environmental science.
Topics & Concepts
NanodotSulfurChemistryFilter paperFilter (signal processing)NanotechnologyChemical engineeringMaterials scienceChromatographyPhysical chemistryOrganic chemistryComputer scienceEngineeringComputer visionCholinesterase and Neurodegenerative DiseasesElectrochemical sensors and biosensorsElectrochemical Analysis and Applications