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Decarboxylative sulfinamidation of <i>N</i> -sulfinylamines with carboxylic acids <i>via</i> a photochemical iron-mediated ligand-to-metal charge transfer process

Dan Yang, Qiang Xiao, Yan Zhou, Hui Zhang, Tingting Chen, Mingsong Shi

2025Chemical Communications11 citationsDOI

Abstract

a photoinduced iron-mediated ligand-to-metal charge-transfer process. Notably, this protocol exemplifies an environmentally benign approach to the synthesis of a range of structurally diverse sulfinamides with an excellent functional group compatibility, thereby rendering it suitable for the late-stage modification of bioactive molecules.

Topics & Concepts

Ligand (biochemistry)ChemistryMetalCharge (physics)PhotochemistryDecarboxylationCarboxylic acidOrganic chemistryCatalysisReceptorPhysicsBiochemistryQuantum mechanicsSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods
Decarboxylative sulfinamidation of <i>N</i> -sulfinylamines with carboxylic acids <i>via</i> a photochemical iron-mediated ligand-to-metal charge transfer process | Litcius