Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity
Yue Zhang, Jiankun Song, Yuanzhang Zhou, Huijun Jia, Tianyu Zhou, Yingbo Sun, Qiong Gao, Yue Zhao, Yujie Pan, Zhaolin Sun, Peng Chu
Topics & Concepts
RottlerinChemistryUbiquitinBiochemistryCancer researchBiologyEnzymeProtein kinase AGeneUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors ResearchCancer-related Molecular Pathways