Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors
Samuel Jurado, Christiane Moog, Mario Cano‐Muñoz, Sylvie Schmidt, Géraldine Laumond, Valentina Ruocco, Sara Standoli, Daniel Polo-Megías, Francisco Conejero‐Lara, Bertrand Morel
Topics & Concepts
Gp41Heptad repeatContext (archaeology)MyristoylationChemistryPlasma protein bindingHuman immunodeficiency virus (HIV)Entry inhibitorBiochemistryBiologyPeptide sequenceBiophysicsMembraneViral entryCell cultureGeneticsVirologyEpitopeGeneAntigenPaleontologyViral replicationHIV Research and TreatmentHIV/AIDS drug development and treatmentRNA and protein synthesis mechanisms