Inhibiting mTOR activity using AZD2014 increases autophagy in the mouse cerebral cortex
Julien Bensalem, Célia Fourrier, Leanne K. Hein, Sofia Hassiotis, Christopher G. Proud, Timothy J. Sargeant
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayNeurodegenerationmTORC2mTORC1Genetically modified mouseULK1Cell biologyMechanistic target of rapamycinTransgeneBiologyNeuroscienceChemistryKinaseProtein kinase ABiochemistrySignal transductionMedicineInternal medicineGeneApoptosisDiseaseAMPKAutophagy in Disease and TherapyCannabis and Cannabinoid ResearchPolyamine Metabolism and Applications